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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3186
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nos3
Name: nitric oxide synthase 3
Acc ID: CHEBI:18088
Term: formononetin
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'.
Chemical ID: MESH:C007768
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos3increases expressionEXP 6480464CTDformononetin results in increased expression of NOS3 mRNA

PMID:19570671
Nos3multiple interactionsEXP 6480464CTDformononetin results in increased phosphorylation of and results in increased activity of NOS3 protein

PMID:19570671
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