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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1
Acc ID: CHEBI:18088
Term: formononetin
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'.
Chemical ID: MESH:C007768
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1affects bindingISORGD:7365596480464CTDformononetin binds to ESR1 protein

PMID:16773531
Esr1multiple interactionsISORGD:7365596480464CTDformononetin binds to and results in increased activity of ESR1 protein

PMID:16076101 PMID:9751507
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