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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350018
Species: Homo sapiens
RGD Object: Gene
Symbol: UGT1A1
Name: UDP glucuronosyltransferase family 1 member A1
Acc ID: CHEBI:18088
Term: formononetin
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'.
Chemical ID: MESH:C007768
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UGT1A1increases expressionEXP 6480464CTDformononetin results in increased expression of UGT1A1 mRNAPMID:37793997
UGT1A1increases glucuronidationEXP 6480464CTDUGT1A1 protein results in increased glucuronidation of formononetinPMID:14557274
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