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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62191
Species: Mus musculus
RGD Object: Gene
Symbol: Maoa
Name: monoamine oxidase A
Acc ID: CHEBI:18086
Term: indol-3-ylacetaldehyde
Definition: An indoleacetaldehyde that is acetaldehyde in which one of the methyl hydrogens are replaced by a indol-3-yl group. It is an intermediate metabolite in the metabolism of tryptophan.
Chemical ID: MESH:C001655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maoaincreases chemical synthesisISOMAOA (Homo sapiens)6480464CTDMAOA protein results in increased chemical synthesis of indole-3-acetaldehydePMID:26686552
Maoamultiple interactionsISOMAOA (Homo sapiens)6480464CTD[[MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehydePMID:26686552
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