Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2053
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Parp1
Name:	poly (ADP-ribose) polymerase 1

Acc ID:	CHEBI:180692
Term:	EUK-134
Definition:	null
Chemical ID:	MESH:C433928

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Parp1	multiple interactions	ISO	PARP1 (Homo sapiens)	6480464	CTD	EUK-134 inhibits the reaction [evodiamine results in increased cleavage of PARP1 protein]	PMID:34808100

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.