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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69426
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oprk1
Name: opioid receptor, kappa 1
Acc ID: CHEBI:180536
Term: 7-Hydroxymitragynine
Definition: null
Chemical ID: MESH:C482678
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oprk1affects bindingISOOPRK1 (Homo sapiens)6480464CTD7-hydroxymitragynine binds to OPRK1 proteinPMID:27192616
Oprk1affects bindingISOOprk1 (Mus musculus)6480464CTD7-hydroxymitragynine binds to OPRK1 proteinPMID:27192616
Oprk1multiple interactionsISOOPRK1 (Homo sapiens)6480464CTD7-hydroxymitragynine inhibits the reaction [3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein]PMID:27192616
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