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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:18009
Term: NADP(+)
Definition: A NAD(P)(+) that has formula C21H29N7O17P3.
Chemical ID: MESH:D009249
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1multiple interactionsEXP 6480464CTD[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP1A1 proteinPMID:24713513
Cyp1a1multiple interactionsISOCYP1A1 (Homo sapiens)6480464CTDNADP promotes the reaction [CYP1A1 protein affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide]PMID:15720144
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