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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10864
Species: Mus musculus
RGD Object: Gene
Symbol: Ldlr
Name: low density lipoprotein receptor
Acc ID: CHEBI:17992
Term: sucrose
Definition: A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose.
Chemical ID: MESH:D013395
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ldlrmultiple interactionsISOLdlr (Rattus norvegicus)6480464CTD[Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR mRNA; [Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR protein; resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR mRNA]; resveratrol inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in decreased expression of LDLR protein]PMID:23127599
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