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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730870
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1A1
Name: cytochrome P450 family 1 subfamily A member 1
Acc ID: CHEBI:17948
Term: (+)-taxifolin
Definition: A taxifolin that has (2R,3R)-configuration.
Chemical ID: MESH:C003377
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1A1increases expressionEXP 6480464CTDtaxifolin results in increased expression of CYP1A1 mRNA; taxifolin results in increased expression of CYP1A1 proteinPMID:22422552 PMID:29584932
CYP1A1multiple interactionsEXP 6480464CTDAHR gene mutant form inhibits the reaction [taxifolin results in increased expression of CYP1A1 mRNA]PMID:29584932
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