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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347893
Species: Homo sapiens
RGD Object: Gene
Symbol: HSD3B1
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Acc ID: CHEBI:17948
Term: (+)-taxifolin
Definition: A taxifolin that has (2R,3R)-configuration.
Chemical ID: MESH:C003377
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSD3B1multiple interactionsISOHsd3b1 (Rattus norvegicus)6480464CTDFluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in decreased expression of HSD3B1 protein]]; taxifolin inhibits the reaction [bisphenol A results in decreased expression of HSD3B1 protein]; taxifolin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HSD3B1 mRNA]; taxifolin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HSD3B1 protein]; taxifolin promotes the reaction [Fluvastatin inhibits the reaction [bisphenol A results in decreased expression of HSD3B1 protein]]PMID:35465754 PMID:36198370
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