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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318375
Species: Mus musculus
RGD Object: Gene
Symbol: Sirt1
Name: sirtuin 1
Acc ID: CHEBI:17948
Term: (+)-taxifolin
Definition: A taxifolin that has (2R,3R)-configuration.
Chemical ID: MESH:C003377
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sirt1multiple interactionsISOSirt1 (Rattus norvegicus)6480464CTDtaxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of SIRT1 protein]; taxifolin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SIRT1 protein]PMID:32525071 PMID:36198370
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