GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ACHE | decreases activity | EXP | | 6480464 | CTD | Isoflurophate results in decreased activity of ACHE protein | PMID:18344198 PMID:20227398 PMID:20888407 PMID:21673941 PMID:24395470 PMID:26965078 PMID:9268605 PMID:9515941 | ACHE | multiple interactions | EXP | | 6480464 | CTD | Fullerenes analog inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; Glucosides inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; Oximes inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein] | PMID:18344198 PMID:20227398 PMID:20888407 | ACHE | decreases activity | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Isoflurophate analog results in decreased activity of ACHE protein; Isoflurophate results in decreased activity of ACHE protein | PMID:1609424 PMID:21513723 PMID:22986948 PMID:26965078 PMID:29272548 PMID:29894704 PMID:3215484 PMID:35500718 PMID:7150809 PMID:7178195 PMID:7234437 PMID:7713347 PMID:8336138 | ACHE | decreases activity | ISO | Ache (Mus musculus) | 6480464 | CTD | Isoflurophate results in decreased activity of ACHE protein | PMID:16978018 PMID:21767560 PMID:22209767 PMID:24395470 PMID:26965078 PMID:28500787 PMID:33176172 PMID:9268605 PMID:9515941 | ACHE | decreases expression | ISO | Ache (Rattus norvegicus) | 6480464 | CTD | Isoflurophate results in decreased expression of ACHE mRNA | PMID:24291005 | ACHE | decreases response to substance | ISO | Ache (Mus musculus) | 6480464 | CTD | ACHE protein results in decreased susceptibility to Isoflurophate; ACHE results in decreased susceptibility to Isoflurophate | PMID:16443250 PMID:17192637 PMID:21783513 | ACHE | multiple interactions | ISO | Ache (Mus musculus) | 6480464 | CTD | Corticosterone inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein]; Isoflurophate binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | PMID:17402711 PMID:28500787 | | ||||||||||||||||||||||
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