Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736747
Species: Homo sapiens
RGD Object: Gene
Symbol: ALDH1A1
Name: aldehyde dehydrogenase 1 family member A1
Acc ID: CHEBI:17898
Term: all-trans-retinal
Definition: A retinal in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D012172
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALDH1A1multiple interactionsEXP 6480464CTD[ALDH1A1 protein co-treated with NAD] results in increased oxidation of Retinaldehyde; ALDH1A1 protein affects the metabolism of [RBP1 protein binds to Retinaldehyde]; ALDH1A1 protein binds to and results in increased oxidation of RetinaldehydePMID:10559215 PMID:23220587
ALDH1A1affects oxidationISOAldh1a1 (Rattus norvegicus)6480464CTDALDH1A1 protein affects the oxidation of RetinaldehydePMID:17167544
ALDH1A1multiple interactionsISOAldh1a1 (Rattus norvegicus)6480464CTDMagnesium Chloride inhibits the reaction [ALDH1A1 protein affects the oxidation of Retinaldehyde]; Magnesium inhibits the reaction [ALDH1A1 protein affects the oxidation of Retinaldehyde]PMID:17167544
Go Back to source page   Continue to Ontology report