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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11411
Species: Mus musculus
RGD Object: Gene
Symbol: Tgfa
Name: transforming growth factor alpha
Acc ID: CHEBI:17883
Term: hydrogen chloride
Definition: A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.
Chemical ID: MESH:D006851
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfaincreases expressionISOTgfa (Rattus norvegicus)6480464CTDHydrochloric Acid results in increased expression of TGFA proteinPMID:15309881
Tgfamultiple interactionsISOTgfa (Rattus norvegicus)6480464CTD[Aspirin co-treated with Hydrochloric Acid] results in increased expression of TGFA mRNA; Celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein]; Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein]; Piroxicam promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein]PMID:15309881 PMID:9726391
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