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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2219
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Brca2
Name: BRCA2, DNA repair associated
Acc ID: CHEBI:17846
Term: (S)-naringenin
Definition: The (S)-enantiomer of naringenin.
Chemical ID: MESH:C005273
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Brca2increases expressionISOBRCA2 (Homo sapiens)6480464CTDnaringenin results in increased expression of BRCA2 mRNAPMID:36235125
Brca2multiple interactionsISOBRCA2 (Homo sapiens)6480464CTD[naringenin co-treated with bisphenol A] results in increased expression of BRCA2 mRNA; [naringenin metabolite co-treated with bisphenol A] results in increased expression of BRCA2 mRNAPMID:36235125
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