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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDGentamicins results in increased expression of DDIT3 mRNA, Gentamicins results in increased expression of DDIT3 protein

PMID:29751043
multiple interactionsEXP 6480464CTDtauroursodeoxycholic acid inhibits the reaction [Gentamicins results in increased expression of DDIT3 mRNA], tauroursodeoxycholic acid inhibits the reaction [Gentamicins results in increased expression of DDIT3 protein]

PMID:29751043
increases expressionISORGD:623916480464CTDGentamicins results in increased expression of DDIT3 mRNA

PMID:18172885, PMID:22061828
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.