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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1622225
Species: Mus musculus
RGD Object: Gene
Symbol: Nr2c2ap
Name: nuclear receptor 2C2-associated protein
Acc ID: CHEBI:17823
Term: calcitriol
Definition: A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.
Chemical ID: MESH:D002117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr2c2apdecreases expressionISONR2C2AP (Homo sapiens)6480464CTDCalcitriol results in decreased expression of NR2C2AP mRNAPMID:21592394
Nr2c2apmultiple interactionsISONR2C2AP (Homo sapiens)6480464CTD[Testosterone co-treated with Calcitriol] results in decreased expression of NR2C2AP mRNAPMID:21592394
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