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RGD ID: 1307337
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wdfy2
Name: WD repeat and FYVE domain containing 2
Acc ID: CHEBI:17823
Term: calcitriol
Definition: A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.
Chemical ID: MESH:D002117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wdfy2increases expressionISORGD:13164746480464CTDCalcitriol results in increased expression of WDFY2 mRNA

Wdfy2multiple interactionsISORGD:13164746480464CTD[Testosterone co-treated with Calcitriol] results in increased expression of WDFY2 mRNA

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.