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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11046
Species: Mus musculus
RGD Object: Gene
Symbol: P4hb
Name: prolyl 4-hydroxylase, beta polypeptide
Acc ID: CHEBI:17823
Term: calcitriol
Definition: A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.
Chemical ID: MESH:D002117
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P4hbmultiple interactionsISOP4hb (Rattus norvegicus)6480464CTD[Calcium co-treated with Calcitriol] affects the expression of P4HB mRNAPMID:15913539
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