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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620735
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tas2r118
Name: taste receptor, type 2, member 118
Acc ID: CHEBI:17814
Term: salicin
Definition: An aryl beta-D-glucoside that is salicyl alcohol in which the phenolic hydrogen has been replaced by a beta-D-glucosyl residue.
Chemical ID: MESH:C005696
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tas2r118increases activityISOTAS2R16 (Homo sapiens)6480464CTDsalicin results in increased activity of TAS2R16 proteinPMID:21629661
Tas2r118multiple interactionsISOTAS2R16 (Homo sapiens)6480464CTD4-((diethylamino)sulfonyl)benzoic acid inhibits the reaction [salicin results in increased activity of TAS2R16 protein]; Probenecid inhibits the reaction [salicin results in increased activity of TAS2R16 protein]PMID:21629661
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