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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70896
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ces1d
Name: carboxylesterase 1D
Acc ID: CHEBI:17763
Term: 4-methylumbelliferyl acetate
Definition: An acetate ester consiting of umbelliferone carrying a 7-O-acetyl group.
Chemical ID: MESH:C032078
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ces1dincreases hydrolysisISORGD:13529606480464CTDCES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate

PMID:9311626
Ces1dmultiple interactionsISORGD:13529606480464CTDAtropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] tropacocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]

PMID:9311626
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