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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621168
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ogg1
Name: 8-oxoguanine DNA glycosylase
Acc ID: CHEBI:17750
Term: glycine betaine
Definition: The amino acid betaine derived from glycine.
Chemical ID: MESH:D001622
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ogg1multiple interactionsISOOgg1 (Mus musculus)6480464CTDBetaine inhibits the reaction [S-Adenosylhomocysteine results in decreased expression of OGG1 protein]; Betaine inhibits the reaction [S-Adenosylhomocysteine results in decreased methylation of OGG1 promoter]PMID:22064374
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