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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730823
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCB1
Name: ATP binding cassette subfamily B member 1
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCB1increases expressionEXP 6480464CTDDiethylhexyl Phthalate results in increased expression of ABCB1 mRNAPMID:17003290
ABCB1multiple interactionsEXP 6480464CTDDiethylhexyl Phthalate promotes the reaction [NR1I2 protein results in increased expression of ABCB1 mRNA]PMID:17003290
ABCB1multiple interactionsISOAbcb1a (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ABCB1A mRNAPMID:28433925
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