Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708482
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dhrs4
Name: dehydrogenase/reductase 4
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7321506480464CTDDiethylhexyl Phthalate results in decreased expression of DHRS4 mRNA

PMID:28085963
increases expressionISORGD:7321506480464CTDDiethylhexyl Phthalate results in increased expression of DHRS4 mRNA

PMID:19850644
multiple interactionsISORGD:7321506480464CTDPPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of DHRS4 mRNA]

PMID:19850644
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.