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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2836
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b1
Name: hydroxysteroid (17-beta) dehydrogenase 1
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b1decreases expressionEXP 6480464CTDDiethylhexyl Phthalate results in decreased expression of HSD17B1 proteinPMID:31369804
Hsd17b1increases expressionEXP 6480464CTDDiethylhexyl Phthalate results in increased expression of HSD17B1 proteinPMID:30090590
Hsd17b1multiple interactionsEXP 6480464CTD[Genistein co-treated with Diethylhexyl Phthalate] results in decreased expression of HSD17B1 mRNAPMID:36674726
Hsd17b1affects expressionISOHsd17b1 (Mus musculus)6480464CTDDiethylhexyl Phthalate affects the expression of HSD17B1 mRNAPMID:25701202
Hsd17b1decreases expressionISOHsd17b1 (Mus musculus)6480464CTDDiethylhexyl Phthalate results in decreased expression of HSD17B1 mRNAPMID:31211961
Hsd17b1increases expressionISOHSD17B1 (Homo sapiens)6480464CTDDiethylhexyl Phthalate results in increased expression of HSD17B1 mRNAPMID:31163220
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