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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1606037
Species: Homo sapiens
RGD Object: Gene
Symbol: DNMT3B
Name: DNA methyltransferase 3 beta
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DNMT3Bdecreases expressionEXP 6480464CTDDiethylhexyl Phthalate results in decreased expression of DNMT3B mRNAPMID:31163220
DNMT3Bincreases expressionEXP 6480464CTDDiethylhexyl Phthalate results in increased expression of DNMT3B proteinPMID:31163220
DNMT3Baffects expressionISODnmt3b (Mus musculus)6480464CTDDiethylhexyl Phthalate affects the expression of DNMT3B mRNAPMID:32628958
DNMT3Bdecreases expressionISODnmt3b (Mus musculus)6480464CTDDiethylhexyl Phthalate results in decreased expression of DNMT3B mRNAPMID:31211961
DNMT3Bincreases expressionISODnmt3b (Rattus norvegicus)6480464CTDDiethylhexyl Phthalate results in increased expression of DNMT3B mRNA; Diethylhexyl Phthalate results in increased expression of DNMT3B proteinPMID:25280772
DNMT3Bincreases expressionISODnmt3b (Mus musculus)6480464CTDDiethylhexyl Phthalate results in increased expression of DNMT3B mRNAPMID:20335514
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