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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1601933
Species: Homo sapiens
RGD Object: Gene
Symbol: UGT3A1
Name: UDP glycosyltransferase family 3 member A1
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UGT3A1decreases expressionEXP 6480464CTDDiethylhexyl Phthalate results in decreased expression of UGT3A1 mRNAPMID:31163220
UGT3A1increases expressionISOUgt3a1 (Mus musculus)6480464CTDDiethylhexyl Phthalate results in increased expression of UGT3A1 mRNAPMID:19850644
UGT3A1multiple interactionsISOUgt3a1 (Mus musculus)6480464CTDPPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of UGT3A1 mRNA]PMID:19850644
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