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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553168
Species: Mus musculus
RGD Object: Gene
Symbol: Slc27a1
Name: solute carrier family 27 (fatty acid transporter), member 1
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc27a1decreases expressionEXP 6480464CTDDiethylhexyl Phthalate results in decreased expression of SLC27A1 mRNAPMID:29753845 PMID:35550907
Slc27a1increases expressionEXP 6480464CTDDiethylhexyl Phthalate results in increased expression of SLC27A1 mRNAPMID:19850644
Slc27a1multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of SLC27A1 mRNA; PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SLC27A1 mRNA]PMID:19850644 PMID:28433925
Slc27a1increases expressionISOSlc27a1 (Rattus norvegicus)6480464CTDDiethylhexyl Phthalate results in increased expression of SLC27A1 mRNA; Diethylhexyl Phthalate results in increased expression of SLC27A1 proteinPMID:15647598
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