GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP51A1 | decreases expression | ISO | Cyp51 (Rattus norvegicus) | 6480464 | CTD | Diethylhexyl Phthalate results in decreased expression of CYP51 mRNA | PMID:26472102 PMID:33983380 | CYP51A1 | increases expression | ISO | Cyp51 (Rattus norvegicus) | 6480464 | CTD | Diethylhexyl Phthalate results in increased expression of CYP51 mRNA | PMID:37560165 | CYP51A1 | increases expression | ISO | Cyp51 (Mus musculus) | 6480464 | CTD | Diethylhexyl Phthalate results in increased expression of CYP51 mRNA | PMID:19850644 | CYP51A1 | multiple interactions | ISO | Cyp51 (Mus musculus) | 6480464 | CTD | [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CYP51 mRNA; [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP51 mRNA; PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of CYP51 mRNA] | PMID:19850644 PMID:28433925 PMID:30722647 | | ||||||||||||||||||||||
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