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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322514
Species: Mus musculus
RGD Object: Gene
Symbol: Sox9
Name: SRY (sex determining region Y)-box 9
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sox9decreases expressionEXP 6480464CTDDiethylhexyl Phthalate results in decreased expression of SOX9 mRNA; Diethylhexyl Phthalate results in decreased expression of SOX9 proteinPMID:26219507 PMID:27060630
Sox9decreases expressionISOSox9 (Rattus norvegicus)6480464CTDDiethylhexyl Phthalate results in decreased expression of SOX9 mRNAPMID:26472102
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