GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc39a5 | increases expression | ISO | SLC39A5 (Homo sapiens) | 6480464 | CTD | Diethylhexyl Phthalate results in increased expression of SLC39A5 mRNA; Diethylhexyl Phthalate results in increased expression of SLC39A5 protein | PMID:36774801 | Slc39a5 | increases expression | ISO | Slc39a5 (Mus musculus) | 6480464 | CTD | Diethylhexyl Phthalate results in increased expression of SLC39A5 mRNA; Diethylhexyl Phthalate results in increased expression of SLC39A5 protein | PMID:19850644 PMID:36774801 | Slc39a5 | multiple interactions | ISO | SLC39A5 (Homo sapiens) | 6480464 | CTD | SLC39A5 protein promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF protein]]; SLC39A5 protein promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of RELA protein]]; SLC39A5 protein promotes the reaction [Diethylhexyl Phthalate results in increased cleavage of CASP1 protein]; SLC39A5 protein promotes the reaction [Diethylhexyl Phthalate results in increased cleavage of GSDMD protein]; SLC39A5 protein promotes the reaction [Diethylhexyl Phthalate results in increased cleavage of IL1B protein]; SLC39A5 protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 mRNA]; SLC39A5 protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] | PMID:36774801 | Slc39a5 | multiple interactions | ISO | Slc39a5 (Mus musculus) | 6480464 | CTD | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of SLC39A5 mRNA] | PMID:19850644 | | ||||||||||||||||||||||
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