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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303135
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Npc1l1
Name: NPC1 like intracellular cholesterol transporter 1
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Npc1l1multiple interactionsISONpc1l1 (Mus musculus)6480464CTD[Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NPC1L1 mRNAPMID:30722647
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