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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303039
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ece2
Name: endothelin-converting enzyme 2
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ece2multiple interactionsEXP 6480464CTD[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ECE2 mRNAPMID:31199487
Ece2decreases expressionISOECE2 (Homo sapiens)6480464CTDDiethylhexyl Phthalate results in decreased expression of ECE2 mRNAPMID:31163220
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