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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731551
Species: Homo sapiens
RGD Object: Gene
Symbol: GCLM
Name: glutamate-cysteine ligase modifier subunit
Acc ID: CHEBI:177406
Term: Bardoxolone methyl
Definition: null
Chemical ID: MESH:C445068
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GCLMdecreases expressionEXP 6480464CTDbardoxolone methyl results in decreased expression of GCLM mRNAPMID:35724838
GCLMincreases expressionEXP 6480464CTDbardoxolone methyl results in increased expression of GCLM; bardoxolone methyl results in increased expression of GCLM mRNAPMID:21723306 PMID:34480604
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