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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349540
Species: Homo sapiens
RGD Object: Gene
Symbol: MT-ND1
Name: mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1
Acc ID: CHEBI:17698
Term: chloramphenicol
Definition: An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions.
Chemical ID: MESH:D002701
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MT-ND1decreases expressionEXP 6480464CTDChloramphenicol results in decreased expression of ND1 mRNAPMID:22712077
MT-ND1multiple interactionsISOmt-Nd1 (Mus musculus)6480464CTDChloramphenicol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of ND1 mRNA]PMID:21767162
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