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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558284
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt1a2
Name: UDP glucuronosyltransferase 1 family, polypeptide A2
Acc ID: CHEBI:17688
Term: (S)-nicotine
Definition: A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt1a2increases glucuronidationISOUGT1A3 (Homo sapiens)6480464CTDUGT1A3 protein results in increased glucuronidation of NicotinePMID:14570768
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