GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmox1 | increases expression | EXP | | 6480464 | CTD | Nicotine results in increased expression of HMOX1 mRNA; Nicotine results in increased expression of HMOX1 protein | PMID:23942037 PMID:24095726 | Hmox1 | increases response to substance | EXP | | 6480464 | CTD | HMOX1 protein results in increased susceptibility to Nicotine | PMID:24095726 | Hmox1 | multiple interactions | EXP | | 6480464 | CTD | [Lipopolysaccharides co-treated with Nicotine] results in increased expression of HMOX1 mRNA; [Lipopolysaccharides co-treated with Nicotine] results in increased expression of HMOX1 protein; [Nicotine co-treated with polylactic acid-polyglycolic acid copolymer] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of ZFP36 mRNA]; HMOX1 protein promotes the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; HMOX1 protein promotes the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of ZFP36 mRNA]]; HMOX1 protein promotes the reaction [Nicotine results in increased expression of ZFP36 mRNA]; HMOX1 protein promotes the reaction [Nicotine results in increased phosphorylation of STAT3 protein]; Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of HMOX1 protein]; STAT3 protein promotes the reaction [[Lipopolysaccharides co-treated with Nicotine] results in increased expression of HMOX1 mRNA] | PMID:23933227 PMID:24095726 | Hmox1 | affects expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | Nicotine affects the expression of HMOX1 mRNA | PMID:22954530 | | ||||||||||||||||||||||
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