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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737222
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp17a1
Name: cytochrome P450, family 17, subfamily a, polypeptide 1
Acc ID: CHEBI:17642
Term: pentachlorophenol
Definition: A chlorophenol that is phenol substituted by 5 chloro groups.
Chemical ID: MESH:D010416
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp17a1increases expressionEXP 6480464CTDPentachlorophenol results in increased expression of CYP17A1 mRNAPMID:23892564
Cyp17a1decreases expressionISOCYP17A1 (Homo sapiens)6480464CTDPentachlorophenol results in decreased expression of CYP17A1 mRNAPMID:21296122
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