Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736559
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR1
Name: estrogen receptor 1
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR1decreases expressionEXP 6480464CTDGlucose results in decreased expression of ESR1 mRNAPMID:16621514
ESR1increases abundanceEXP 6480464CTDESR1 protein results in increased abundance of GlucosePMID:31520823
ESR1increases expressionEXP 6480464CTDGlucose results in increased expression of ESR1 mRNAPMID:16621514
ESR1increases phosphorylationEXP 6480464CTDGlucose results in increased phosphorylation of ESR1 proteinPMID:23690508
ESR1multiple interactionsEXP 6480464CTDEndosulfan promotes the reaction [ESR1 protein results in increased abundance of Glucose]PMID:31520823
ESR1multiple interactionsISOEsr1 (Rattus norvegicus)6480464CTD[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA; ESR1 protein promotes the reaction [[Resveratrol results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose]; tetrahydropalmatine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA]PMID:18426865 PMID:37606869
Go Back to source page   Continue to Ontology report