GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Apoe | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of APOE mRNA; Glucose results in decreased expression of APOE protein | PMID:34485530 | Apoe | multiple interactions | EXP | | 6480464 | CTD | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of APOE mRNA; morroniside inhibits the reaction [Glucose results in decreased expression of APOE mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of APOE protein] | PMID:34485530 PMID:37567420 | Apoe | affects secretion | ISO | APOE (Homo sapiens) | 6480464 | CTD | Glucose deficiency affects the secretion of APOE protein | PMID:24802182 | |
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