Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733604
Species: Mus musculus
RGD Object: Gene
Symbol: Apoe
Name: apolipoprotein E
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoedecreases expressionEXP 6480464CTDGlucose results in decreased expression of APOE mRNA; Glucose results in decreased expression of APOE proteinPMID:34485530
Apoemultiple interactionsEXP 6480464CTD[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of APOE mRNA; morroniside inhibits the reaction [Glucose results in decreased expression of APOE mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of APOE protein]PMID:34485530 PMID:37567420
Apoeaffects secretionISOAPOE (Homo sapiens)6480464CTDGlucose deficiency affects the secretion of APOE proteinPMID:24802182
Go Back to source page   Continue to Ontology report