GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NOX4 | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of NOX4 protein | PMID:31494106 | NOX4 | multiple interactions | EXP | | 6480464 | CTD | [Glucose co-treated with TGFB1 protein] results in increased expression of NOX4 protein; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of NOX4 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of NOX4 protein] | PMID:31494106 PMID:35961541 | NOX4 | increases expression | ISO | Nox4 (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of NOX4 mRNA; Glucose results in increased expression of NOX4 protein | PMID:31838053 | NOX4 | multiple interactions | ISO | Nox4 (Rattus norvegicus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of NOX4 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOX4 mRNA; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of NOX4 mRNA]; diphenyliodonium inhibits the reaction [Glucose results in increased expression of NOX4 protein]; farrerol inhibits the reaction [Glucose results in increased expression of NOX4 mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of NOX4 protein] | PMID:29702141 PMID:31838053 | | ||||||||||||||||||||||
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