GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MMP2 | multiple interactions | EXP | | 6480464 | CTD | Glucose promotes the reaction [Air Pollutants results in increased activity of MMP2 protein]; Glucose promotes the reaction [Air Pollutants results in increased expression of MMP2 mRNA]; Glucose promotes the reaction [Particulate Matter results in increased activity of MMP2 protein]; Glucose promotes the reaction [Particulate Matter results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Air Pollutants results in increased activity of MMP2 protein]]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Particulate Matter results in increased activity of MMP2 protein]] | PMID:26179980 | MMP2 | decreases expression | ISO | Mmp2 (Rattus norvegicus) | 6480464 | CTD | Glucose results in decreased expression of MMP2 mRNA; Glucose results in decreased expression of MMP2 protein | PMID:31838053 | MMP2 | increases activity | ISO | Mmp2 (Mus musculus) | 6480464 | CTD | Glucose results in increased activity of MMP2 protein | PMID:24659233 | MMP2 | increases expression | ISO | Mmp2 (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of MMP2 mRNA; Glucose results in increased expression of MMP2 protein | PMID:18665442 | MMP2 | multiple interactions | ISO | Mmp2 (Rattus norvegicus) | 6480464 | CTD | farrerol inhibits the reaction [Glucose results in decreased expression of MMP2 mRNA]; farrerol inhibits the reaction [Glucose results in decreased expression of MMP2 protein]; Rosiglitazone inhibits the reaction [Glucose results in increased expression of MMP2 mRNA]; Rosiglitazone inhibits the reaction [Glucose results in increased expression of MMP2 protein] | PMID:18665442 PMID:31838053 | MMP2 | multiple interactions | ISO | Mmp2 (Mus musculus) | 6480464 | CTD | CEBPB protein inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of MMP2 protein]; Glucose results in decreased expression of and results in decreased activity of MMP2 protein; Resveratrol inhibits the reaction [Glucose results in increased activity of MMP2 protein]; Valsartan inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of MMP2 protein] | PMID:24659233 PMID:29266779 | | ||||||||||||||||||||||
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