GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sphk1 | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of SPHK1 mRNA | PMID:21998146 | Sphk1 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein]; Glucose results in increased expression of and results in increased activity of SPHK1 protein; N,N-dimethylsphingosine inhibits the reaction [Glucose results in increased activity of SPHK1 protein]; Pyridoxamine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein]; SPHK1 mRNA affects the reaction [Glucose results in increased expression of FN1 protein]; SPHK1 protein inhibits the reaction [Glucose results in increased expression of FN1 protein] | PMID:21998146 | |
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