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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3395
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkca
Name: protein kinase C, alpha
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkcamultiple interactionsEXP 6480464CTDGlucose promotes the reaction [zinc chloride affects the localization of and results in increased activity of PRKCA protein]PMID:20800666
Prkcaincreases phosphorylationISOPRKCA (Homo sapiens)6480464CTDGlucose results in increased phosphorylation of PRKCA proteinPMID:22162761
Prkcamultiple interactionsISOPrkca (Mus musculus)6480464CTD[Glucose co-treated with Silymarin] results in increased phosphorylation of PRKCA protein; Glucose promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of PRKCA protein]PMID:29753610
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