GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gcg | decreases secretion | EXP | | 6480464 | CTD | Glucose results in decreased secretion of GCG protein | PMID:12914525 | Gcg | increases abundance | EXP | | 6480464 | CTD | GCG results in increased abundance of Glucose | PMID:19002567 | Gcg | increases secretion | EXP | | 6480464 | CTD | Glucose results in increased secretion of GCG protein | PMID:15919803 | Gcg | multiple interactions | EXP | | 6480464 | CTD | 9-phenanthrol inhibits the reaction [[GCG protein co-treated with Glucose] results in increased secretion of INS1 protein]; [GCG protein co-treated with Glucose] results in increased secretion of INS1 protein; [GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; Metformin inhibits the reaction [GCG results in increased abundance of Glucose]; Troglitazone inhibits the reaction [Glucose results in decreased secretion of GCG protein]; Zinc inhibits the reaction [Glucose results in increased secretion of GCG protein] | PMID:12914525 PMID:15919803 PMID:18669601 PMID:19002567 PMID:29098165 | Gcg | increases secretion | ISO | Gcg (Mus musculus) | 6480464 | CTD | Glucose results in increased secretion of GCG protein | PMID:22479612 | Gcg | multiple interactions | ISO | Gcg (Mus musculus) | 6480464 | CTD | [GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; isosteviol inhibits the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]]; Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein] | PMID:18669601 PMID:22479612 | Gcg | multiple interactions | ISO | GCG (Homo sapiens) | 6480464 | CTD | Glucose inhibits the reaction [[Niacin results in decreased abundance of Fatty Acids, Nonesterified] which results in increased secretion of GCG protein] | PMID:838844 | | ||||||||||||||||||||||
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