GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MAFA | multiple interactions | EXP | | 6480464 | CTD | 3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]; 3-aminobenzamide inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]]; Niacinamide inhibits the reaction [Glucose inhibits the reaction [MAFA protein binds to INS promoter]] | PMID:16505238 | MAFA | affects expression | ISO | Mafa (Rattus norvegicus) | 6480464 | CTD | Glucose affects the expression of MAFA mRNA | PMID:24349266 | MAFA | increases expression | ISO | Mafa (Mus musculus) | 6480464 | CTD | Glucose results in increased expression of MAFA mRNA | PMID:22558381 | MAFA | increases expression | ISO | Mafa (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of MAFA mRNA | PMID:22558381 | MAFA | multiple interactions | ISO | Mafa (Mus musculus) | 6480464 | CTD | IL1B protein inhibits the reaction [Glucose results in increased expression of MAFA mRNA]; lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]; Palmitic Acid inhibits the reaction [Glucose results in increased expression of MAFA mRNA]; TLR4 affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA]] | PMID:22558381 | MAFA | multiple interactions | ISO | Mafa (Rattus norvegicus) | 6480464 | CTD | 3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose results in decreased expression of MAFA mRNA]; 3,4-dihydro-5-methyl-1(2H)-isoquinolinone inhibits the reaction [Glucose results in decreased expression of MAFA protein]; 3-aminobenzamide inhibits the reaction [Glucose results in decreased expression of MAFA mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in decreased expression of MAFA protein]; lipopolysaccharide, Escherichia coli O111 B4 inhibits the reaction [Glucose results in increased expression of MAFA mRNA] | PMID:16505238 PMID:22558381 | |
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