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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1587390
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkg1
Name: protein kinase cGMP-dependent 1
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkg1decreases expressionEXP 6480464CTDGlucose results in decreased expression of PRKG1 mRNAPMID:17320767
Prkg1multiple interactionsEXP 6480464CTDacetovanillone inhibits the reaction [Glucose results in decreased expression of PRKG1 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in decreased expression of PRKG1 protein]; Glucose results in decreased expression of and results in decreased activity of PRKG1 protein; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased expression of PRKG1 protein]; Reactive Oxygen Species promotes the reaction [Glucose results in decreased expression of PRKG1 protein]; tempol inhibits the reaction [Glucose results in decreased expression of PRKG1 protein]PMID:17320767
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