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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348698
Species: Homo sapiens
RGD Object: Gene
Symbol: NCF1
Name: neutrophil cytosolic factor 1
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NCF1affects localizationEXP 6480464CTDGlucose affects the localization of NCF1 proteinPMID:17916771
NCF1increases expressionEXP 6480464CTDGlucose results in increased expression of NCF1 proteinPMID:18088078
NCF1multiple interactionsEXP 6480464CTDacetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of NCF1 protein]; bisindolylmaleimide I inhibits the reaction [Glucose affects the localization of NCF1 protein]; Glucose results in increased expression of and results in increased activity of NCF1 protein; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of NCF1 protein]; PRKAA1 protein affects the reaction [rosiglitazone inhibits the reaction [Glucose affects the localization of NCF1 protein]]; rosiglitazone inhibits the reaction [Glucose affects the localization of NCF1 protein]PMID:17916771 PMID:18088078 PMID:19878672
NCF1increases expressionISONcf1 (Rattus norvegicus)6480464CTDGlucose results in increased expression of NCF1 mRNA; Glucose results in increased expression of NCF1 proteinPMID:12821678 PMID:22245600 PMID:26054749
NCF1increases phosphorylationISONcf1 (Rattus norvegicus)6480464CTDGlucose results in increased phosphorylation of NCF1 proteinPMID:24971582
NCF1multiple interactionsISONcf1 (Rattus norvegicus)6480464CTD[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein; [[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of and results in increased phosphorylation of NCF1 protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of NCF1 protein]]; Glucose results in increased expression of and results in increased phosphorylation of NCF1 protein; NCF1 protein promotes the reaction [Glucose results in increased chemical synthesis of Reactive Oxygen Species]; NCF1 protein promotes the reaction [Glucose results in increased expression of FN1 protein]; pyrazolanthrone inhibits the reaction [Glucose results in increased expression of NCF1 protein]; Resveratrol inhibits the reaction [[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of NCF1 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of NCF1 protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of NCF1 protein]PMID:17320767 PMID:22245600 PMID:24971582 PMID:26054749
NCF1multiple interactionsISONcf1 (Mus musculus)6480464CTD[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of NCF1 mRNAPMID:37567420
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