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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345644
Species: Homo sapiens
RGD Object: Gene
Symbol: MIR217
Name: microRNA 217
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MIR217increases expressionISORGD:23255476480464CTDGlucose results in increased expression of MIR217 mRNA

PMID:26891083
MIR217multiple interactionsISORGD:23255476480464CTDMIR217 mRNA affects the reaction [Glucose results in decreased expression of SIRT1 mRNA], MIR217 mRNA affects the reaction [Glucose results in decreased expression of SIRT1 protein], MIR217 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein], MIR217 mRNA affects the reaction [Glucose results in increased expression of EDN1 protein], MIR217 mRNA affects the reaction [Glucose results in increased expression of FN1 protein], MIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A mRNA], MIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A protein], MIR217 mRNA affects the reaction [Glucose results in increased expression of TGFB1 protein], MIR217 mRNA affects the reaction [Glucose results in increased expression of VEGFA protein]

PMID:26891083
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.