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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343937
Species: Homo sapiens
RGD Object: Gene
Symbol: S1PR2
Name: sphingosine-1-phosphate receptor 2
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S1PR2increases expressionISOS1pr2 (Rattus norvegicus)6480464CTDGlucose results in increased expression of S1PR2 mRNAPMID:22406263
S1PR2multiple interactionsISOS1pr2 (Rattus norvegicus)6480464CTD[JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; [JTE 013 binds to and results in decreased activity of S1PR2 protein] results in decreased susceptibility to [sphingosine 1-phosphate co-treated with Glucose]PMID:22406263
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